Paul Karpecki, OD, FAAO
Director of Research, Moyes Eye Clinic, Kansas City, MO
Many of our allergy patients have challenges staying in their contact lens during the spring season. This may be because their eyes are continuously itching or the antihistamine they're taking is causing additional drying of the ocular surface. Patients are adamant about staying in their lenses even during the spring. Studies have already shown that oral antihistamines can be drying, but what about the ocular eye drops.
A study conducted in 2006 compared the Elestat® (epinastine HCl 0.05%) to Claritin® (loratadine) in a 4 day cross-over study. Several outcomes were measured including: tear volume, tear flow, and corneal staining. After 4 days of twice daily use of Elestat® there was NO change in tear volume, tear flow, and corneal staining. Elestat® had a remarkable neutral impact on the ocular surface. However, after 4 days once daily use of loratadine there was a significant decrease in tear volume, tear flow and an increase in corneal staining.
What this means for your patients that are contact lens users, those who have dry eyes or individuals that are taking any P.O. allergy medications, instilling Elestat® will soothe their eyes and not exacerbate the dryness they currently feel.
References
D. Andrew Workman, George W. Ousler, Gail L. Torkidsen M.D. An Evaluation of the Ocular Drying Effect of a Systemic Anthistamine (Loratadine) Compared to a Topical Anthistamine (Epinastine) Poster Accepted to ASCRS 2007.